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 | Francis William Sprague (1600-1670) |
 | Lydia ? Archer (1602-1660) |
| Ann Sprague (1620-1669) |
| Mercy (Marcy) Sprague (1622- )  |
| John Sprague, Sr. (1633-1676) |
| Dorcas Sprague (1629- ) |
| Mary Sprague (1625- ) |
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